基本信息
 高爽
性 别: 出生年月: 1978-08-31
职 称: 教授 工作单位: 文理学院化学系
硕导(招生学科): 应用化学 博导(招生学科):
办公电话: 0451-55190974 E-mail: gaoshuang@neau.edu.cn
 开设课程情况
课程编号 课程名称 课程类别 学时
20600005g 普通化学 公共课 56
20600038j 仪器分析 公共课 32
20600116x 仪器分析 公共课 32
20600017g 分析化学Ⅰ 公共课 32
20610004g 化学实验 公共课 96
20610038j 仪器分析实验 公共课 32
20610039j 仪器分析实验 专业课 64
 主持科研项目概况
1、 国家自然科学基金,31801784,基于ALS除草剂的取代磺酰胺二氮(氧)杂二环类安全剂设计、合成及活性研究,2019/01-2021/12,24万元,在研,主持
2、 哈尔滨市科技创新人才基金,2017RAQXJ017、新型取代氧氮杂桥环类安全剂的设计、合成与构效研究,2017/09-2019/08,10万元,在研,主持
3、 黑龙江省博士后资助经费,LBH-Z16030,新型取代氧氮杂桥环类安全剂的设计、制备及修复机制研究,2017.01-2018.12 ,5万元,在研,主持
4、 黑龙江省自然科学基金面上项目,C2015013,取代氮氧杂环安全剂保护玉米免受除草剂药害的酶诱导作用研究,2014/01-2016/12,6万元,结题,主持。
5、 黑龙江省教育厅科学技术研究项目,12531027,安全剂保护玉米免受ALS除草剂药害的酶活性诱导及解毒机制研究,2013/01-2015/12,2万元,结题,主持。
6、 市科技创新人才项目,2010RFQYN108,新型除草剂安全剂二氯乙酰基噁唑烷的手性拆分与应用,2010/01-2012/12,2.7万元,结题,主持。
 项目获奖概况

1. 基于分子碎片重组设计的农用功能分子及其作用机制研究,2020.黑龙江省科学技术奖,二等奖(4)

2. 安全剂保护作物免受除草剂药害研究,2016. 08, 黑龙江省科学技术奖,二等奖(4)

3. 安全剂保护作物免受除草剂药害研究,2016.02, 年黑龙江省农业科技奖,一等奖(4)

 代表性著作、论文

1. Shuang Gao, Yanyan Liu, Jingyu Jiang, Xiaoming Li, Fei Ye*, Ying Fu* and Lixia Zhao, Thiram/hydroxypropyl-β-cyclodextrin inclusion complex electrospun nanofibers for a fast dissolving water-based drug delivery system. Colloids and Surfaces B: Biointerfaces, 2021, https://doi.org/10.1016/j.colsurfb.2021.111625(SCI)IF=4.389 (二区)

2. Tao Kang, Shuang Gao, Li-Xia Zhao, Yue Zhai, Fei Ye*, and Ying Fu*. Design, synthesis and SAR of novel 1,3-disubstituted imidazolidine or hexahydropyrimidine derivatives as herbicide safeners. Journal of Agricultural and Food Chemistry, 2021, 69(1):45-54(SCI)IF=4.192 (一区)

3. Shuang Gao, Jingyu Jiang, Xiaoming Li, Fei Ye*, Ying Fu1* and Lixia Zhao. An Environmentally Safe Formulation with Enhanced Solubility and Fungicidal Activity: Self-assembly and Characterization of Difenoconazole-β-CD Inclusion Complex. Journal of Molecular Liquids, 2020,(SCI)IF=4.564 (二区)

4. L. Lu, G. Shuang, Y. Liu, L. Yu-Long, L. Ping, Y. Fei, F. Ying, Cobalt (II) complex as a fluorescent sensing platform for the selective and sensitive detection of triketone HPPD inhibitors, Journal of Hazardous Materials, 2021,404: 124015(SCI)IF=9.038 (一区)

5. Liu, Y; Gao, S; Yang, L ; Liu, YL; Liang, XM; Ye, F; Fu, Y. A Highly Selective Perylenediimide-Based Chemosensor: "Naked-Eye" Colorimetric and Fluorescent Turn-On Recognition for Al3+ . Frontiers in chemistry, 2020, 8: 702.(SCI)IF=3.693 (二区)

6. Zhang, YY; Gao, S; Hoang, MT; Wang, ZW; Ma, X; Zhai, Y; Li, N; Zhao, LX; Fu, Y; Ye, F. Protective efficacy of phenoxyacetyl oxazolidine derivatives as safeners against nicosulfuron toxicity in maize, Pest Management Science , DOI: 10.1002/ps.6005, IF= [3.75] (一区)

7. Gao, S; Liu, YY; Jiang, JY; Li, XM; Zhao, LX; Fu, Y; Ye, F. Encapsulation of thiabendazole in hydroxypropyl-beta-cyclodextrin nanofibers via polymer-free electrospinning and its characterization, Pest Management Science, 2020,76(9): 3264-3272, IF=3.75 (一区)

8. Liu, YX; Gao, S ; Ye, T; Li, JZ; Ye, F; Fu, Y. Combined 3D-quantitative structure-activity relationships and topomer technology-based molecular design of human 4-hydroxyphenylpyruvate dioxygenase inhibitors, Future Medicinal Chemistry, 2020,12(9): 795-811.(SCI)IF=3.607 (二区)

9. Zhang Y-Y, Gao S, Liu Y-X, Wang C, Jiang W, Zhao L-X, et al., Design, Synthesis, and Biological Activity of Novel Diazabicyclo Derivatives as Safeners. Journal of Agricultural and Food Chemistry 2020, 68: 3403-3414 (SCI)IF=4.192 (一区)

10. Shuang Gao, Jingyu Jiang, Xiaoming Li, Yanyan Liu, Lixia Zhao, Ying Fu, Fei Ye. Enhanced physicochemical properties and herbicidal activity of an environment-friendly clathrate formed by β-cyclodextrin and herbicide cyanazine. Journal of Molecular Liquids, 2020,305, 112858. https://doi.org/10.1016/j.molliq.2020.112858(SCI)IF=4.564 (二区)

11. Gao, S.; Jiang, J.-Y.; Liu, Y.-Y.; Fu, Y.; Zhao, L.-X.; Li, C.-Y.; Ye, F. Enhanced Solubility, Stability, and Herbicidal Activity of the Herbicide Diuron by Complex Formation with β-Cyclodextrin. Polymers 2019, 11, 1396. (SCI)IF=3.164 (二区)

12. Shuang Gao , Yan-Yan Liu, Jing-Yu Jiang, Ying Fu, Li-Xia Zhao, Chun-Yan Li and Fei Ye. Protective Responses Induced by Chiral 3-Dichloroacetyl Oxazolidine Safeners in Maize (Zea mays L.) and the Detoxification Mechanism. Molecules 2019, 24, 3060; doi:10.3390/molecules24173060(SCI)IF=3.060 (三区)

13. Gao, S.; Bie, C.; Ji, Q.Y.; Ling, H.Y.; Li, C.Y.; Fu, Y.; Zhao, L.X.; Ye, F., Preparation and characterization of cyanazine–hydroxypropyl-beta-cyclodextrin inclusion complex. RSC Adv. 2019, 9, 26109-26115. (SCI)IF=3.049 (三区)

14. Gao, S.; Liu, Y. Y.; Jiang, J. Y.; Ji, Q. Y.; Fu, Y.; Zhao, L. X.; Li, C. Y.; Ye, F. Physicochemical properties and fungicidal activity of inclusion complexes of fungicide chlorothalonil with β-cyclodextrin and hydroxypropyl-β-cyclodextrin. Journal of Molecular Liquids, 2019, 293, 111513. doi:10.1016/j.molliq.2019.111513. (SCI)IF=4.564 (二区)

15. Shuang Gao, Chao Bie, Yanyan Liu, Tianyu Zhang, Ying Fu and Fei Ye*.Functional Supramolecular of Inclusion Complex of Herbicide Fluroxypyr with HPβCD. Polymers, 2018, 10, 1294(SCI)IF=3.364 (二区)

16. Gao Shuang, Wang Yuxin, Jiang Bin, Fu Ying*. Application of problem-based learning in instrumental analysis teaching at Northeast Agricultural University. Analytical and Bioanalytical Chemistry,2018, 410(16):3621-3627(SCI)IF=3.307

17. Fei Ye ; Hai-Feng Cao; Li-Na Wei; Chen Wang; Ying Fu; Chun-Yan Li; Shuang Gao*. Chiral 3-dichloroacetyl oxazolidines induced the activity of enzymes in maize for the detoxified herbicide, International Journal of Agriculture and Biology,2018,20,1027-1032(SCI)IF=0.869

18. Fei YE, Hai-Feng Cao, Xue-Song Chen, Meng ZHANG, Ying FU, Chun-Yan LI and Shuang GAO*.Effects of chiral 3-dichloroacetyl oxazolidine on glutathione S-transferase and antioxidant enzymes activity in maize treated with acetochlor,Tarim Bilimleri Dergisi-Journal of Agricultural Sciences. 2018,24(3): 422-429(SCI)IF=0.261

19. Gao, Shuang ; Bie, Chao; Chen, Xue-Song; Zhao, Li-Xia; Fu, Ying; Li,Chun-Yan; Ye, Fei *. Inducing Glutathione S-Transferase Expression and Activity using an Herbicide Safener against Metolachlor in Maize , International Journal of Agriculture and Biology, 2017, 19(6): 1357-1362.(SCI)IF=0.746

20. Gao, Shuang, Qu, Hai-Tao, Ye, Fei,Fu, Ying. Synthesis and Crystal Structure of N-Dichloroacetyl-3,4-dihydro-3-methyl-6-chloro-2H-1,4- benzoxazine; Journal of Chemistry; 2015, vol2015: 1-5.(SCI)IF=0.996

21. Shuang Gao, Ying Fu, Li-Xia Zhao, Zhi-Yong Xing,Fei Ye. Synthesis and Crystal Structure of Novel Chiral N-dichloroacetyl-2-substituted-5-methyl-1,3-oxazolidines; Heterocycles; 2012, 85(4):903-910.(SCI)IF=1.107

22. Shuang Gao, Li-Xia Zhao, Fei Ye, Ying Fu. 1-Dichloroacetyl-8a-methyl-1,2,3,4,6,7,8,8a-octahydro;Acta Cryst; 2012, E68(o1982) (SCI)IF=0.367

23. Fu, Ying, Kang, Jing-XinWang, Yun-Kai, Liu, Jing, Zhao, Li-Xia, Gao, Shuang,Ye, Fei;Design, Synthesis and Biological Activity of Novel Sulfonylurea Oxazolidines; Heterocycles; 2016, 92(4):740-750;(SCI)IF=1.107

24. Fei YE,Hai-Feng CAO, Ying FU, Li-Xia ZHAO, Shuang GAO. The safener effect of chiral derivatives of 3-dichloroacetyl oxazolidine against haloxyfop-P-methyl- induced toxicity in maize; Zemdirbyste-Agriculture;2016, 103(1):29-33;(SCI)IF=0.579

25. Li-xia Zhao, Hai-Tao Qu, Ying Fu, Shuang Gao, Fei Ye. Alleviation of injury from chlorimuron-ethyl in maize treated with safener 3-dichloroacetyl oxazolidine. Canadian Journal of Plant Science; 2015; 95: 1-7;(SCI) IF=0.727

26. Fei Ye, Fei Yang, Li-Xia Zhao, Shuang Gao, Ying Fu. Synthesis and crystal structure of novel N-acyl-2,3-dimethyl-3,4-2H-1,4- benzoxazine. Journal of Chemical Research. 2015, 39:357-359(SCI) IF=0.596

27. Fei Ye, Shi-Long Wu, Li-Xia Zhao, Hai-Tao Qu, Shuang Gao, and Ying Fu*. Synthesis and Safener Activity of Novel Substituted 4-Phenoxyacetyl-1,4-benzoxazines. Heterocycles. 2015, 91(6):1256-1268;(SCI)IF=1.107

28. Fei Ye, Shi-Long Wu, Shuang Gao, and Ying Fu*; Synthesis, Crystal Structure and Biological Activity of Novel Substituted N-Acetoxyacetyl-3-methyl-3,4-dihydro-2H-1,4-benzoxazine; Indian Journal of Heterocyclic Chemistry, 2015, 24(4): 481-486;(SCI)IF=0.207

29. Fei Ye, Fei Yang, Li-Xia Zhao, Shuang Gao and Ying Fu*; Synthesis and crystal structure of cis-N-acetoxyacetyl-2,3-dimethyl-3,4-dihydro-2H-1,4- benzoxazine; Indian Journal of Heterocyclic Chemistry, 2015, 25(2):126-132;(SCI)IF=0.207

30. Li-Xia Zhao,Ying Fu,Shuang Gao, Zhi-Yong Xing, Li-Na Wei, and Fei Ye*; Protective Responses Induced by 3-Dichloroacetyl Oxazolidine Safeners in Maize(Zeamays) International Journal of Agriculture and Biology; 2014,16(6):1204-1208;(SCI)IF=0.758

31. Fei Ye, Ying Li, Ying Fu,* Shuang Gao and Li-Xia Zhao; Microwave-Assisted Synthesis and Crystal Structure Of Novel 2-Dichloromethyl-1,3-Dioxolane Heterocycles; 2013,87(2): 407-415;(SCI)IF=1.107

32. 赵李霞,刘程国, 付颖, 高爽, 叶非*; 安全剂R-28725保护玉米免受氯磺 隆药害的作用研究; 植物保护; 2013, 39(1): 29-32;

33. Fei Ye, Cheng-Guo Liu, Xin-Ming Wang, Ying Fu*, Shuang Gao. A Convenient one-pot Synthesis of N-Dichloroacetyl-5-aryl-1,3-oxazolidines; Heterocyclic Communications; 2013; 19(3): 201-205;(SCI)IF=0.828

34. Fei Ye, Ying Li, Ying Fu*, Li-Xia Zhao, Shuang Gao, and Zhi-Yong Xing. Synthesis and crystal structure of 2-dichloromethyl-2-phenyl-1,3-dioxolane; Indian Journal of Heterocyclic Chemistry; 2013, 22(4): 349-352;(SCI)IF=0.207

35. Fei Ye, Shuang Gao, Ying Fu* , Xin-Ming Wang and Zhi-Yong Xing; Synthesis and biological studies of some novel 2-substituted-3-dichloroacetyl-1,3-oxazolidines. Indian Journal of Heterocyclic Chemistry; 2012, 21(3): 277-280;(SCI)IF=0.207

36. Li-Xia Zhao, Cheng-Guo Liu, Ying Fu, Zhi-Yong Xing, Fei Ye *, Shuang Gao; Induction of maize glutathione S-transferase by herbicide safener and their effect on enzyme activity against chlorsulfuron; Advanced Materials Research; 2012, 518-523:5480-5483;(EI)

37. Fei Ye, Ying Li, Ying Fu, Li-Xia Zhao and Shuang Gao; 1-(6-Bromo-3,4-dihydro -2H-1,4- benzoxazin-4-yl)-2,2-dichloroethanone, Acta Crystallographica, Section E, 2012,, E68, o2509;(SCI)IF=0.367

38. Ying Fu, Li-hua Qu, Shan-Shan Zhang, Fei Ye,* Li-xia Zhao, Shuang Gao, Zhi-Yong Xing; Simple and Efficient Synthesis of Novel N-Dichloroacetyl-3,4-dihydro-2H- 1,4-benzoxazines; Heterocyclic Communications; 2012; 18(3):143–146;(SCI)IF=0.828

39. Ying Fu, Hai-tao Li, Fei Ye*, Shuang Gao, Qing-Shan Zhao; Quantitative structure-activity relationship study on a novel series of N-dichloroacetyl oxazolidine herbicide Safeners; Indian Journal of Heterocyclic Chemistry; 2012, 21(4):375-380;(SCI)IF=0.207

40. Li-Xia Zhao, Ying Fu,Fei Ye,* Shuang Gao. A Mild and Highly Efficient Synthesis of Chiral N-DichloroacetylA-1,3-Oxazolidines; Journal of Heterocyclic Chemistry; 2012, 49(4):943-946;(SCI)IF=0.685

41. Ying Fu,Lei Yang,Fei Ye* and Shuang Gao; One-Pot Microwave-Assisted Synthesis of Novel Substituted N-Dichloroacetyl-4,5-dimethyl- 1,3-Oxazolidines; Journal of Heterocyclic Chemistry; 2012,49(5):1235-1238;(SCI)IF=0.685 .

42. Zhao, Li-Xia, Fu, Ying, Ye, Fei, Gao, Shuang; Synthesis and crystal structure of (R)-(-)-N-dichloroacetyl-3-ethyl-1-oxa-4-aza- spiro-4.5-decane; Heterocyclic Communications; 2011,17(1-2):53-55;(SCI)IF=0.828

 授权的专利等情况

1. 一种含有喹喔啉结构的三酮类化合物、制备方法及其应用,发明专利, ZL   201911193040.1,第3发明人
2. 一种含肉桂酰基的三酮类化合物、制备方法及其应用,发明专利,ZL201911191742.6,第3  发明人
3. 用于玉米生长的区域防治有害杂草的除草组合物及其用途,发明专利,ZL201810750196.4,第4发明人
4. 一种化学实验用的冰浴器,实用新型专利 ZL 2012 2 0114401.6 ,第1发明人
5. 一种容量瓶,实用新型专利 ZL 2012 2 0114390.1 ,第1发明人

 其他获奖及荣誉称号