基本信息
 李一经
性 别: 出生年月: 1960-11-01
职 称: 教授 工作单位: 动物医学学院
招生学科1: 预防兽医学 招生学科2:
办公电话: E-mail:
 开设研究生课程情况
课程编号 课程名称 课程级别 学时
微生物病原学 72
兽医细菌学专题 72
高级兽医微生物学 72
 近五年主持科研项目概况

1. 主持“十二五”863项目子课题,猪腹泻性疫病新型分子诊断技术研究与产品开发/2012AA101304, 143.3万元,2012.1.1-2015.12.30

2. 主持“十二五”863项目子课题,动物梭菌类疾病安全级重组乳酸菌活菌载体疫苗创制及工艺创新/2011AA10A213, 80.8万元。 2011.1.1-2015.12.30

3. 主持“十一五” 国家科技支撑计划,李斯特菌快速检测技术研究/2010BAD04B02,40万元,2010.1.1-2012.12.31

4. 主持黑龙江省十二五攻关项目,猪腹泻相关疾病新型疫苗与诊断试剂工艺创新及其应用/GC12B3032012.1.1-2015-12-3130

5.黑龙江省高等学校科技创新团队,猪重要腹泻性疾病致病机制及其防治关键技术研究,2011-2015100万元

5、主持国家自然科学基金“转基因乳酸菌表面展示猪轮状病毒保护性抗原及诱导黏膜免疫的研究”,20031-201612月,81

 近五年项目获奖概况

1.获黑龙江科技发明二等奖,获奖名称:“猪传染性胃肠炎快速检测试剂的研制及其应用”,获奖人员:李一经、唐丽杰、师东方、葛俊伟、任晓峰、姜骞,刘玉芬、王新生,2007.8

2. 获黑龙江高校科学技术一等奖,获奖名称:猪腹泻病毒重要基因及其结构蛋白免疫相关功能的研究,获奖人员:李一经、任晓峰、刘敏、尹杰超、葛俊伟、唐丽杰、乔薪瑗、姜艳平、崔文,2010.4.9

 近五年代表性著作、论文

1Xinyuan Qiao,Guiwei Li,Xiangqing Wang,Xiaojing Li, Min Liu,and Yijing Li*Recombinant porcine rotavirus VP4 and VP4-LTB expressed in Lactobacillus casei induced mucosal and systemic antibody responses in mice, BMC Microbiol. 2009; 9: 249. SCI收录)

   2Yi-jing Li, Guang-peng Ma, Gui-wei Li, Xin-yuan Qiao, Jun-wei Ge, Li-jie Tang, Min Liu, Li-wei Liu, Oral Vaccination with the Porcine Rotavirus VP4 Outer Capsid Protein Expressed by Lactococcus lactis Induces Specific Antibody Production,  Journal of Biomedicine and Biotechnology, Volume2010,(SCI收录)

3. Liu D, Wang X, Ge J, Liu S, Yijing Li*Comparison of the immune responses induced by oral immunization of mice with Lactobacillus casei-expressing porcine parvovirus VP2 and VP2 fused to Escherichia coli heat-labile enterotoxin B subunit protein Comp Immunol Microbiol Infect Dis, 2011, 34: 73-81SCI收录)

4. Liu Songmei, Liu Didi, Zhang Guanqun, Li Yijing*, Intragastric administratiion of lastobacillus casei expressing bovine rotavirus VP7 protein induced specifie antibody production, iCBBE 2010, 2010,6 (EI 收录)

5. Di-Qiu L, Xin-Yuan Q, Jun-Wei G, Li-Jie T, Yan-Ping J, Yijing Li*.Construction and characterization of Lactobacillus pentosus expressing the D antigenic site of the spike protein of Transmissible gastroenteritis virusCan J Microbiol2011;57(5):392-7SCI收录)

6. Xu Y, Cui L, Tian C, Zhang G, Huo G, Tang L, Yijing Li*.Immunogenicity of recombinant classic swine fever virus CD8(+) T lymphocyte epitope and porcine parvovirus VP2 antigen coexpressed by Lactobacillus casei in swine via oral vaccination. Clin Vaccine Immunol. 2011, 18(11):1979-86. SCI收录)

7. Di-Qiu L, Jun-Wei G, Xin-Yuan Q, Yan-Ping J, Song-Mei L, Yijing Li*.High-level mucosal and systemic immune responses induced by oral administration with Lactobacillus-expressed porcine epidemic diarrhea virus (PEDV) S1 region combined with Lactobacillus-expressed N protein. Appl Microbiol Biotechnol. 2011 Dec 2. [Epub ahead of print] SCI收录)

8. Min L, Li-Li Z, Jun-Wei G, Xin-Yuan Q, Yijing Li*, Immunogenicity of Lactobacillus-expressing VP2 and VP3 of the infectious pancreatic necrosis virus (IPNV) in rainbow trout. Fish Shellfish Immunol. 2012 Jan;32(1):196-203SCI收录)

9. Li-Li Z, Min L, Jun-Wei G, Xin-Yuan Q, Yijing Li*, Expression of infectious pancreatic necrosis virus (IPNV) VP2-VP3 fusion protein in Lactobacillus casei and immunogenicity in rainbow trouts. Vaccine. 2012 Jan 9. [Epub ahead of print] SCI收录)

 近五年授权的专利等情况

表达猪传染性胃肠炎病毒S蛋白的重组乳酸球菌及制法,国家发明专利,唐丽杰、李一经、葛俊伟、欧笛,专利号:ZL 2007 10089251.1 2009129

 其他获奖及荣誉称号