基本信息
 李艳华
性 别: 出生年月: 1970-10-10
职 称: 教授 工作单位: 东北农业大学
招生学科1: 基础兽医学 招生学科2:
办公电话: 0451-55191881 E-mail: liyanhua1970@163.com
 开设研究生课程情况
课程编号 课程名称 课程级别 学时
兽医药理学研究班讨论 36
 近五年主持科研项目概况


1.“十二五”国家科技支撑项目 抗猪链球菌病复方制剂的研制 ,50万,主持
2.国家自然基金项目 丁香叶干预2 型猪链球菌生物被膜形成的有效成分及其对cps基因簇调控研究,84万,主持
3.“十二五”国家科技支撑项目 防治猪流感中兽药的研制与开发,140万,主持
4.教育部博导联合基金 大环内酯类药物对猪链球菌体内生物被膜作用及对QS 系统影响的研究,6万,主持
5.哈尔滨市创新人才研究专项 大环内酯类药物对猪链球菌生物被膜QS系统信号分子AI-2、CSP的影响,3万,主持
6.黑龙江省留学归国人员科学基金 大环内酯类药物对猪链球菌生物被膜QS信号分子的作用,5万,主持
7.黑龙江省教育厅科学技术研究项目 大环内酯类药物对猪链球菌体外生物被膜的作用及毒力因子影响,2万,主持

 近五年项目获奖概况

2014.8 黑龙江省科学技术发明奖 一等奖(8)
2013.12 黑龙江省科学技术发明奖 二等奖(1)
2013.03 黑龙江省畜牧科学技术奖 一等奖(1)
2014.10 中国畜牧兽医学会兽医药理毒理学分会第十三次学术讨论会 优秀论文奖(通讯作者)
2012.10 中国畜牧兽医学会兽医药理毒理学分会第十二次学术讨论会 优秀论文奖(通讯作者)
2012.10 中国畜牧兽医学会兽医药理毒理学分会第十二次学术讨论会 优秀论文奖(通讯作者

 近五年代表性著作、论文

[1] Yang YB, Wang S, Wang C, Huang QY, Bai JW, Chen JQ, Chen XY, Li YH*..Emodin affects biofilm formation and expression of virulence factors in Streptococcus suis ATCC700794. Archives of microbiology .DOI 10.1007/s00203-015-1158-4(SCI)
[2] Yu-Lin Zhao, Yong-Hui Zhou, Jian-Qing Chen, Quan-Yong Huang, Qiang Han, Bing Liu, Guang-Dong Cheng, Yan-Hua Li*.Quantitative proteomic analysis of sub-MIC erythromycin inhibiting biofilm formation of S. suis in vitro. Journal of Proteomics. Vol (116), 1-14, 2015(SCI)
[3] P.F Wan, Z.L Sheng, Q Han, Y.L Zhao, G.D Cheng, Y.H Li*.Enrichment and purification of total flavonoids from Flos Populi extracts with macroporous resins and evaluation of antioxidant activities in vitro, J Chromatogr B, Vol(945), No. 1,68-74,2014(SCI)
[4] G.D Cheng, Y.L Zhao, H Li, Y Wu, X.X Li, Q Han, C.S Dai, Y.H Li*. Forsythiaside attenuates lipopolysaccharide induced inflammatory responses in the bursa of Fabricius of chickens by downregulating the NFκB signaling pathway, Experimental and Therapeutic Medicine,Vol(7),No. 1, 179–184, 2014(SCI)
[5] Z.L Sheng, P.F Wan, C.L Dong, YH Li*. Optimization of total flavonoids content extracted from Flos Populi using response surface methodology, Ind Crop Prod, Vol(43), No. 5, 778-786, 2013(SCI)
[6] X Gao, G Xu, Y Liu, J.Q Chen, Y Cui, G.D Cheng, Q.B Yan, Y.H Li*. Validation of a UPLC/MS/MS method for determination of compound amoxicillin and tylosin in swine plasmaand its application in a pharmacokinetic study, Journal of Pure and Applied Microbiology, Vol(7 )No. 11, 655-662 , 2013(SCI)
[7] Z.L Sheng, J.C Li, Y.H Li*. Optimization of forsythoside extraction from Forsythia suspensa by Box-Behnken design, African Journal of Biotechnology, Vol(55), No. 10,11728-11737, 2011(SCI)
[8] Z.L Sheng, Y.X Wang, P.F. Wan, Y.H. Li*. Ultrasound-assisted extraction of total flavonoids from Leaves of Syringa Oblata Lindl. Latin American Applied Research, Vol (44), No.2, 131-132,2014(SCI)
[9] Chang Wang, Yan-hua Li* Berberine affects biofilm formation and expression of luxS and virulence factors in Streptococcus suis. Journal of Microbiology and Biotechnology(SCI)(under review)
[10] J Liu, Y.H Li * , Y.L Zhao. Biofilm formation by Streptococcus suis:Modulation by macrolides and four β-lactams antibiotics by different ways.The 6th International Conference on Bioinformatics and Biomedical Engineering. p456-461. Shanghai.2012.10.4-7(EI)
[11] Y.H Li, M.Y Li, L C, Z.L Sheng. 2011. The effects of ethanol extracts from Forsythia suspense against antibiotic-resistant Streptococcus suis isolates in vivo and in vitro. The 5th International Conference on Bioinformatics and Biomedical Engineering. p324-328. Wuhan. 2011.05.10-12(EI)
[12] Z.L Sheng, Y.H Li * . 2011. In vitro antibacterial activity of medicinal herb extracts against five drug-resistant Streptococcus Suis strains. The 5th International Conference on Bioinformatics and Biomedical Engineering .p1-4. Wuhan. 2011.05.10-12(EI)
[13]Shuai Wang, Yanbei Yang, Yulin Zhao, Honghai Zhao, Jingwen Bai, Jianqing Chen, Yonghui Zhou, Chang Wang, Yanhua Lia. Sub-MIC tylosin inhibits Streptococcus suis biofilm formation and results in differential protein expression[J].Frontiers in Microbiology.Vol(7 )No. 3, 655-672 , 2016(SCI)

 近五年授权的专利等情况

中国 ZL 2009 10159913.7 发明专利 猪链球菌耐药抑制剂

中国 ZL 2009 10118153.5 发明专利 预防或治疗猪链球菌病的药物组合物


中国 ZL 201206325311.4  发明专利  丁香叶或其提取物在制备抗猪流感病毒药物中的用途

 其他获奖及荣誉称号

2015.10 黑龙江省青年科技奖

2014.9 哈尔滨市青年科技奖

2014.3 东北农业大学巾帼女杰

2013.3 东北农业大学优秀女教工

2012.9 东北农业大学教学先锋岗