基本信息
 李辉
性 别: 出生年月: 1963-06-01
职 称: 教授 工作单位: 动物科学技术学院学院
招生学科1: 动物遗传育种与繁殖 招生学科2:
办公电话: 0451-55191516 E-mail: lihui@neau.edu.cn
 开设研究生课程情况
课程编号 课程名称 课程级别 学时
5.510 现代养禽 硕士 36
5.501 动物遗传育种硕士研究生班讨论 硕士 72
5.005 家禽育种 博士 56
5.003 动物遗传育种博士研究生班讨论 博士 72
 近五年主持科研项目概况

1.国家自然科学基金重点项目

项目名称:鸡脂肪组织生长的分子遗传学基础(编号:30430510),130万,本人为项目主持人,2005-2008

2.黑龙江省自然科学基金重点项目

项目名称:鸡脂肪细胞分化转录因子基因的功能研究(编号:ZJN0604-01),10万,本人为项目主持人,2007-2009

完成人排序:第一

3.国家973项目

项目名称:猪、鸡重要经济性状遗传的分子机制(No.2006CB102100)。课题名称:重要复杂性状的比较基因组(No.2006CB102105),课题总经费383万元,本人经费96万元,本人为课题第二主持人,2006-2010

4.国家863重大项目

项目名称:主要动植物功能基因组研究。课题名称:家鸡重要经济性状功能基因组研究(2006AA10A120),课题总经费565万元,本人经费115万元,本人为课题副主持人, 2006-2010

5.国家转基因生物新品种培育重大专项课题

课题名称:高通量基因克隆技术体系的研究(2008ZX08009-002);任务名称:影响猪、牛、羊生长与肉质等性状的功能基因的高通量克隆鉴定技术;子任务名称:羊毛品质性状关键基因的高通量筛选和克隆,76万元,本人为子任务主持人,2008-2011

6.国家现代农业产业技术体系建设项目

项目名称:国家肉鸡产业技术体系(No.CARS-42)210万元,本人为岗位专家,2008-2010

7.国家高技术研究发展计划(863)项目子课题

项目名称:主要动植物功能基因组研究;课题名称:优质速长型白羽黄鸡全基因组选择育种研究(编号:2010AA10A102,21万元,本人为课题子任务负责人,2010-2011

8.黑龙江省高等学校科技创新团队建设计划项目

团队名称:家禽遗传育种创新团队;项目名称:鸡生长和体组成性状的功能基因组,200万元,本人为团队负责人和项目主持人,2010-2013

9.国家现代农业产业技术体系建设项目

项目名称:国家肉鸡产业技术体系(No.CARS-42)350万元,本人为岗位专家,2011-2015

10.国家高技术研究发展计划(863)项目

项目名称:鸡重要经济性状的功能基因组学研究(2013AA102501)1028万,本人为课题主持人,2013-2017

 近五年项目获奖概况

1.2010,“鸡脂肪组织生长发育的分子遗传学基础”, 2010年黑龙江省高校科学技术一等奖,排名第一。证书编号:2010-018-1

2.2010,“畜禽良种资源综合利用支撑技术的研究”,2010年黑龙江省科技进步二等奖,排名第三。证书编号:2010-084-03

3.2013,“低脂肉鸡种质资源创新及脂肪发育分子遗传学研究”,2013年黑龙江省科学技术奖一等奖,排名第一。证书号2013-008-04

 近五年代表性著作、论文

1.Y. Wang, Y. Mu, H. Li, N. Ding, Q. Wang, Y. Wang, S. Wang, and N. Wang. Peroxisome Proliferator-Activated Receptor-γGene: A Key Regulator of Adipocyte Differentiation in Chickens. Poultry Science, 2008,87(2)226-232.

2.X. Liu, H. Zhang, H. Li, N. Li, Y. Zhang, Q. Zhang, S. Wang, Q. Wang, and H. Wang. Fine-Mapping Quantitative Trait Loci for Body Weight and Abdominal Fat Traits: Effects of Marker Density and Sample Size. Poultry Science, 2008, 87(7):1314–1319.

3.L. H. Bian, S. Z. Wang, Q. G. Wang, S. Zhang, Y. X. Wang & H. Li. Variation at the insulin-like growth factor 1 gene and its association with body weight traits in the chicken. J. Anim. Breed. Genet., 2008, 125(4):265-270.

4.Hui Zhang, Shouzhi Wang, Hui Li, Xijiang Yu, Ning Li, Qin Zhang, Xiaofeng Liu, Qigui Wang, Xiaoxiang Hu, Yuxiang Wang, and Zhiquan Tang. Microsatellite Markers Linked to Quantitative Trait Loci Affecting Fatness in Divergently Selected Chicken Lines for Abdominal Fat. Asian-Aust. J. Anim. Sci., 2008, 21(10):1389-1394.

5.L. Leng, S. Wang, Z. Li , Q. Wang , and H. Li. A polymorphism in the 3-flanking region of insulin-like growth factor binding protein 2 gene associated with abdominal fat in chickens. Poultry Science, 2009, 88: 938-942.

6.Shuang Liu, Li Wang, Ning Wang, Yuxiang Wang, Hui Shi, Hui Li. Oleate induces transdifferentiation of chicken fibroblasts into adipocyte-like cells. Comparative Biochemiostry and physiology-Part A Molecular & Integrative physiology, 2009, 154 (1): 135-141.

7.Wang, N. Wang, N. Li, and H. Li. Identification of differentially expressed proteins in adipose tissue of divergently selected broilers. Poultry Science, 2009, 88: 2285-2292.

8.H. Shi, Q. Wang, Q. Zhang, L. Leng, and H. Li. Tissue expression characterization of chicken adipocyte fatty acid-binding protein and its expression difference between fat and lean birds in abdominal fat tissue. Poultry Science, 2010, 89 :197–202.

9.Jianwei Tian, Shouzhi Wang, Qigui Wang, Li Leng, Xiaoxiang Hu, and Hui Li. A Single Nucleotide Polymorphism of Chicken Acetyl-Coa Carboxylase A Gene Associated with Fatness Traits. Animal Biotechnology, 2010, 21: 42-50.

10.H. B. Wang, Q. G. Wang, X. Y. Zhang, X. Y. Zhang, X. F. Gu, N. Wang, S. B. Wu and H. Li. Microarray analysis of genes differentially expressed in the liver of lean and fat chickens. Animal, 2010, 4 (4): 513-522.

11.Shuang Liu, Yuxiang Wang, Li Wang, Ning Wang, Yumao Li, Hui Li. Transdifferentiation of Fibroblasts into Adipocyte-like Cells by Chicken Adipogenic Transcription Factors. Comparative Biochemiostry and physiology-Part A Molecular & Integrative physiology, 2010, 156 (4): 502-508.

12.Guo Hu, ShouZhi Wang, JianWei Tian, LiLi Chu, Hui Li. Epistatic effect between ACACA and FABP2 gene on abdominal fat traits in broilers. J. Genet. Genomics, 2010, 37: 505512.

13.G. Hu, S. Z. Wang, Z. P. Wang, Y. M. Li, and H. Li  Genetic epistasis analysis of 10 peroxisome proliferator-activated receptor  -correlated genes in broiler lines divergently selected for abdominal fat content. Poultry Science,2010, 89: 2341-2350.

14.H. Zhang, Y. D. Zhang, S. Z. Wang, X. F. Liu, Q. Zhang, Z. Q. Tang & H. Li. Detection and fine mapping of quantitative trait loci for bone traits on chicken chromosome one. Journal of animal breeding and genetics, 2010, 127, 462–468.

15.Hui Shi, Qigui Wang, Yuxiang Wang, Li Leng, Qingqiu Zhang, Zhouchun Shang, Hui Li. Adipocyte fatty acid-binding protein: An important gene related to lipid metabolism in chicken adipocytes. Comparative Biochemistry and Physiology, Part B, 2010, 157, 357-363.

16.Ning Ding, Yuan Gao, Ning Wang, Hui Li. Functional analysis of the chicken PPARγ gene 5-flanking region and C/EBPα-mediated gene regulation. Comparative Biochemistry and Physiology, Part B, 2011, 158, 297303.

17.Jing Yao, Yuxiang Wang, Weishi Wang, Ning Wang, and Hui Li. Solexa sequencing analysis of chicken pre-adipocyte microRNAs. Biosci. Biotechnol. Biochem., 2011, 75(1): 54-61.

18.H. Zhang, S. H. Liu, Q. Zhang, Y. D. Zhang, S. Z. Wang, Q. G. Wang, Y. X. Wang, Z. Q. Tang & H. Li. Fine-mapping of quantitative trait loci for body weight and bone traits and positional cloning of the RB1 gene in chicken. J. Anim. Breed. Genet. 2011,128: 366–375.

19.H. Shi, Q. Zhang, Y. Wang, P. Yang, Q. Wang, and H. Li. Chicken adipocyte fatty acid-binding protein knockdown affects expression of peroxisome proliferator-activated receptor γgene during oleate-induced adipocyte differentiation. Poultry Science, 2011  90:1037-1044.

20.L. Guo, B. Sun, Z. Shang, L. Leng, Y. Wang, N. Wang, and H. Li. Comparison of adipose tissue cellularity in chicken lines divergently selected for fatness. Poultry Science, 2011, 90: 2024-2034.

21.Hui Zhang, Xiaoxiang Hu, Zhipeng Wang, Yuandan Zhang, Shouzhi Wang, Ning Wang, Li Ma, Li Leng, Shengwen Wang, Qigui Wang, Yuxiang Wang, Zhiquan Tang, Ning Li, Yang Da, Hui Li. Selection Signature Analysis Implicates the PC1/PCSK1 Region for Chicken Abdominal Fat Content. PLoS ONE, 2012 7(7): e40736. doi:10.1371/ journal.pone. 0040736.

22.S.Z. Wang, X.X. Hu, Z.P. Wang, X.C. Li, Q.G. Wang, Y.X. Wang, Z.Q. Tang and H. Li.  Quantitative trait loci associated with body weight and abdominal fat traits on chicken chromosomes 3, 5 and 7. Genetics and Molecular Research, 2012, 11 (2): 956-965.

23.Hui Zhang, Shou-Zhi Wang, Zhi-Peng Wang, Yang Da, Ning Wang, Xiao-Xiang Hu, Yuan-Dan Zhang, Yu-Xiang Wang, Li Leng, Zhi-Quan Tang and Hui Li. A genome-wide scan of selective sweeps in two broiler chicken lines divergently selected for abdominal fat content. BMC Genomics 2012, 13:704 doi:10.1186/1471-2164-13-704.

24. Zhiwei Zhang, Haixia Wang, Yingning Sun, Hui Li, and Ning Wang. Klf7 modulates the differentiation and proliferation of chicken preadipocyte. Acta Biochim Biophys Sin 2013, 45: 280–288.

25. Zhi-Wei ZHANG, Zhi-Peng WANG, Kun ZHANG, Ning WANG and Hui LI. Cloning, tissue expression and polymorphisms of chicken Krüppel-like factor 7 gene. Animal Science Journal, 2013, 84: 535–542.

26.Q. Zhang, H. Shi, W. Liu, Y. Wang, Q. Wang and H. Li. Differential expression of L-FABP and L-BABP between fat and lean chickens.Genet. Mol. Res., 2013, 12 (4): 4192-4206.

26. Yufang Zhao, Enguang Rong, Shouzhi Wang, Hui Zhang, Li Leng, Yuxiang Wang, Qigui Wang and Hui Li. Identification of SNPs of the L-BABP and L-FABP and their Association with Growth and Body Composition Traits in Chicken. J. Poult. Sci., 2013, 50: 300-310.

27.Fangge Li, Guo Hu, Hui Zhang, Shouzhi Wang, Zhipeng Wang and Hui Li. Epistatic Effects on Abdominal Fat Content in Chickens: Results from a Genome-Wide SNP-SNP Interaction Analysis. PLoS ONE, 2013, 8(12): e81520.

 近五年授权的专利等情况

李辉,田建伟;专利名称:一种用ACCα基因预示和鉴定鸡腹脂量的分子标记方法;专利申请日:2009318日;专利权人:东北农业大学;发明专利申请号:200910071572.8,2009;证书号:第875823号;专利号:ZL 2009 1 0071572.8;授权公告日:2011127日。

 其他获奖及荣誉称号

1.2008年被评为黑龙江省优秀中青年专家。